Currie Lab

Current Lab Members

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Jennifer Bratburd

Grad Student

Area of Study

Metabolite Mediated Colonization Resistance in the Humanized Mouse Gut

Research Description

Bio
Jenny Bratburd graduated from University of California, Berkeley in 2014 with a B.S. in Microbial Science and began the Microbial Doctoral Training Program at UW Madison that same year. Jenny has always had an interest in host-microbe interactions, worked with viruses and bacteria in plants in her undergrad, and now microbiota and mouse models in graduate school. In her free time, Jenny likes to adventure outdoors, sailing in the summer and ice-skating in the winter.

Research Interests
An important function of the gut microbiota is to prevent pathogens from colonizing the host. The microbiota confers colonization resistance in a variety of ways, including competition for nutrients and production of small molecules to inhibit pathogens. Some small moleucles from probiotic strains are known to inhibit pathogens; however, the microbiome contains numerous biosynthetic genes that suggest many more compounds are yet to be discovered that could play important roles in human health.

Jenny is interested in exploring the human gut microbiota as a source of anti-pathogenic small molecules. She is using a combination of techniques, including genomics, metabolomics, and proteomics to find out what kinds of compounds the gut microbiota are making.

Publications

  1. Blaisdell, G., Zhang, S., Bratburd, J., Daane, K., Cooper, M. and Almeida, R. (2015) Interactions Within Susceptible Hosts Drive Establishment Of Genetically Distinct Variants Of An Insect-Borne Pathogen. J Econ Entomol, 108, 1531-1539.http://dx.doi.org/10.1093/jee/tov153.

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Currie Labotatory
Feedback/Questions

Location
6145 Microbial Science Building
1550 Linden Drive
Madison, WI 53706
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Contact Info
Lab phone: (608) 890-0237
Fax: (608) 262-9865